The initiative will bolster research to accelerate the development of innovative medications to treat opioid addiction, explore non-addictive interventions for chronic pain, and improve overdose prevention and treatment strategies, including research into additional overdose reversal medications and breathing stimulation devices. In April 2018, NIH announced the Helping to End Addiction Long-term SM Initiative, or NIH HEAL Initiative SM, a trans-agency effort to speed scientific solutions to stem the national opioid public health crisis. While the National Institute on Drug Abuse (NIDA) leads NIH research efforts on drug use and addiction, and the National Institute of Neurological Disorders and Stroke (NINDS) leads NIH research efforts on pain, many of NIH’s Institutes and Centers are involved in these research areas. NIH conducts and supports extensive research on pain management, and drug use and misuse. Results from the 2018 National Survey on Drug Use and Health showed that an estimated 1.2 million people in the United States aged 12 and older had an opioid use disorder, the most recent year for which data are available. Paralleling a rapid increase in rates of opioid pain reliever prescribing, which is now showing early signs of abating, widespread use and misuse of these medications led to an alarming rise in opioid overdose deaths, giving way to a nationwide crisis. However, regular use can lead to dependence, and misuse of opioid pain relievers can lead to addiction, overdose incidents and possibly, death.
Opioid pain relievers can be effective in treatment for relieving pain. These drugs activate opioid receptors on nerve cells in the body and brain. Opioids are a class of drugs that include pain relievers available legally by prescription, the illegal drug heroin, and synthetic opioids such as fentanyl. Opioids The Opioid Crisis NIH and the Opioid Crisis Opioids and Chronic Pain NIH Funding NIH Pain Consortium Images Soundbites Opioids
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